Everything about Xxyy Syndrome totally explained
48,XXYY syndrome is a
sex chromosome anomaly. It affects one in every 17,000 male births. It was previously considered to be a variation of
Klinefelter's syndrome. Common features include tall stature,
gynecomastia, truncal obesity, skin ulcers, and a craniofacial dysmorphism described as a "
pugilistic" facial appearance.
The first published report of a boy with a 48,XXYY karyotype was by Sylfest Muldal and Charles H. Ockey in
Manchester,
England in 1960.
It was found in a 15-year-old mentally challenged boy who had signs of Klinefelter syndrome, eventually, it appeared that he didn't have the Klinefelter Syndrome but, as shown above, the XXYY syndrome.
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